Necrotizing Enterocolitis, An Issue of Clinics in Perinatology

This special issue of Clinics in Perinatology focuses exclusively on Necrotizing Enterocolitis (NEC), a critical and complex condition affecting neonates. Guest editors have curated a comprehensive collection of articles that provide both foundational knowledge and the latest advances in the prevention, diagnosis, and management of NEC. The issue addresses the full clinical spectrum—from feeding strategies to surgical interventions—highlighting evidence-based practices and emerging research to guide optimal neonatal care.

Key Features

• Comprehensive coverage of NEC, including pathophysiology, clinical presentations, and risk factors in both preterm and full-term neonates.
• In-depth discussion on feeding practices, gut microbiome modulation, and the use of prebiotics, probiotics, postbiotics, and lactoferrin.
• Exploration of short gut syndrome, intestinal transplantation, and long-term outcomes following NEC.
• Highlights innovative monitoring techniques, such as Near-Infrared Spectroscopy, to predict NEC risk.
• Detailed review of inflammatory signaling pathways and potential biomarkers for early detection.
• Practical guidance on surgical management and decision-making strategies.
• Written by leading neonatology experts, synthesizing current research, clinical experience, and evidence-based recommendations.